The effect of mass mosquito trapping on malaria transmission and disease burden (SolarMal): a stepped-wedge cluster-randomised trial

Odour baits can attract host-seeking Anopheles mosquitoes indoors and outdoors. We assessed the effects of mass deployment of odour-baited traps on malaria transmission and disease burden. The unexpectedly low clinical incidence of malaria during roll-out led to an imprecise estimate of effectiveness from the clinical incidence data. The substantial effect on malaria prevalence is explained by reduction in densities of Anopheles funestus. Odour-baited traps might be an effective malaria intervention.

Author: , , , , , , , , , , , , ,
Publication date: September 2016
Source: The Lancet

The effect of mass mosquito trapping on malaria transmission and disease burden (SolarMal): a stepped-wedge cluster-randomised trial

Odour baits can attract host-seeking Anopheles mosquitoes indoors and outdoors. This study assessed the effects of mass deployment of odour-baited traps on malaria transmission and disease burden.

Author: , , , , , , , , , , , , ,
Publication date: August 2016
Source: The Lancet

Primaquine to reduce transmission of Plasmodium falciparum malaria in Mali: a single-blind, dose-ranging, adaptive randomised phase 2 trial

Single low doses of primaquine, when added to artemisinin-based combination therapy, might prevent transmission of Plasmodium falciparum malaria to mosquitoes. A single dose of 0·25 mg/kg primaquine, given alongside dihydroartemisinin–piperaquine, was safe and efficacious for the prevention of P falciparum malaria transmission in boys and men who are not deficient in G6PD

Author: , , , , , , , , , , , , , , , , , , ,
Publication date: June 2016
Source: The Lancet Infectious Diseases

The potential impact of adding Ivermectin to a mass treatment intervention to reduce malaria transmission: a modelling study

Ivermectin (IVM), used alongside mass treatment strategies with an artemisinin combination therapy, has been suggested as a possible tool for reducing malaria transmission. Mosquitoes ingesting a bloodmeal containing IVM have increased mortality, reducing the probability that the parasite completes sporogony.

Author: , , , ,
Publication date: June 2014
Source: The Journal of Infectious Diseases

Scale-up of Malaria Rapid Diagnostic Tests and Artemisinin-Based Combination Therapy: Challenges and Perspectives in Sub-Saharan Africa

An article examining the operational challenges to of scaling up and maintaining RDT coverage as needed for the WHO GMP initiative: T3: Test. Treat. Track.

Author: , ,
Publication date: January 2014
Source: PLOS Medicine