Results from this study demonstrate that Tanzania’s national guidelines—which forbid malaria diagnosis through RDT or microscopy in the “private retail sector”—may be unnecessarily curbing testing and treatment rates, given the high proportion of patients seeking private sector care.
This article, published in Nature found that Plasmodium falciparum infection prevalence in endemic Africa halved and the incidence of clinical disease fell by 40% between 2000 and 2015. Interventions have averted an estimated 663 (542–753 credible interval) million clinical cases since 2000. Insecticide-treated nets, the most widespread intervention, were by far the largest contributor (68% of cases averted).
Author: Battle KE, Bennett A, Bhatt S, Bisanzio D, Briet O, Cameron E, Cibulskis RE, Cohen JM, Dalrymple U, Eckhoff P, Eisele TP, Fergus CA, Gething PW, Griffin JT, Hay SI, Henry A, Lindgren F, Lynch M, Mappin B, Moyes CL, Murray CLJ, Penny MA, Smith DL, Smith TA, Weiss J, Wenger E, Yukich J
Publication date: September 2015
This article outlines some of the barriers to single low-dose (SLD) primaquine use to stop P. falciparum transmission. In-country key informants revealed that the WHO weight-based recommendation to use SLD primaquine is challenging to implement in actual field settings, due in part to safety concerns involving G6PD deficiency and drug-drug interactions, among other factors.
A study arguing that active case detection is not a cost-effective strategy to deal with asymptomatic carriers in low transmission settings and that, until new tools are developed, mass drug administration approaches should be pursued.