Imported Plasmodium falciparum and locally transmitted Plasmodium vivax: cross-border malaria transmission scenario in northwestern Thailand

Cross-border malaria transmission is an important problem for national malaria control programs. The epidemiology of cross-border malaria is further complicated in areas where Plasmodium falciparum and Plasmodium vivax are both endemic. By combining passive case detection data with entomological data, a transmission scenario on the northwestern Thai–Myanmar border where P. falciparum is likely driven by importation was described, whereas P. vivax is also locally transmitted. This study highlights the differences in the level of control required to eliminate P. falciparum and P. vivax from the same region.

Author: , , , , , , ,
Publication date: June 2017
Source: Malaria Journal

Population genomics studies identify signatures of global dispersal and drug resistance in Plasmodium vivax

Signals of natural selection suggest that P. vivax is evolving in response to antimalarial drugs and is adapting to regional differences in the human host and the mosquito vector.

Author: , , , , , , , , , , , , , , , , , , , , , , , ,
Publication date: June 2016
Source: Nature Genetics

Clinical Efficacy of Dihydroartemisinin–Piperaquine for the Treatment of Uncomplicated Plasmodium falciparum Malaria at the China–Myanmar Border

This study was conducted from March 2012 to December 2013 in four clinics and seven villages along the China–Myanmar border. The presence of gametocytes in patients through 14 days after DHA-P treatment suggests that the incorporation of a single dose of primaquine for clearing gametocytemia should be considered for blocking parasite transmission.

Author: , , , , , , , , , ,
Publication date: March 2015
Source: AJTMH