This meeting report presents the outcomes of a workshop held in Bangkok on December 1st 2014, where the following challenges were discussed: the threat of resistance to artemisinin and artemisinin-based combination therapy in the Greater Mekong Sub-region (GMS) and in Africa; access to treatment for most at risk and hard to reach population; insecticide resistance, residual and outdoors transmission.
Emergence of artemisinin resistance in Southeast Asia poses a serious threat to the global control of Plasmodium falciparum malaria. Currently, artemisinin resistance extends across much of Myanmar. P falciparum parasites carrying K13-propeller mutations were recorded at high prevalence next to the northwestern border with India. Appropriate therapeutic regimens should be tested urgently and implemented comprehensively if spread of artemisinin resistance to other regions is to be avoided.
Author: Anderson TJC, Ashley EA, Cheah PY, Day NP, Dhorda M, Dondorp AM, Faiz MA, Flegg JA, Grist EPM, Guerin P, Hlaing T, Hlaing TM, Imwong M, Kyaw MP, Lin K, Lwin KM, Maude RJ, McDew-White M, Nair S, Nosten F, Plewes K, Pukrittayakamee S, Smithuis F, Tun KM, White NJ, Win AA, Woodrow CJ
Publication date: February 2015
Source: The Lancet Infectious Diseases