Limitations of Rapid Diagnostic Testing in Patients with Suspected Malaria: A Diagnostic Accuracy Evaluation from Swaziland, a Low-Endemicity Country Aiming for Malaria Elimination

An investigation into the diagnostic accuracy of histidine-rich protein 2–based RDTs using qualitative polymerase chain reaction (PCR) (nested PCR targeting the cytochrome b gene) and quantitative PCR as reference standards.

Author: , , , , , , , , , , , ,
Publication date: March 2017
Source: Clinical Infectious Diseases

Towards malaria elimination in the MOSASWA (Mozambique, South Africa and Swaziland) region

MOSASWA, launched in 2015, seeks to renew regional efforts to accelerate progress towards malaria elimination goals already established in the region. National malaria programmes, together with developmental partners, academic institutions and the private sector seek to harmonize policy, strengthen capacity, share expertise, expand access to elimination interventions particularly amongst migrant and border population groups, mobilize resources and advocate for long-term funding to ultimately achieve and sustain malaria elimination in the MOSASWA region.

Author: , , , , , ,
Publication date: August 2016
Source: Malaria Journal

Development of a pharmacovigilance safety monitoring tool for the rollout of single low-dose primaquine and artemether-lumefantrine to treat Plasmodium falciparum infections in Swaziland: a pilot study

Improved pharmacovigilance to monitor and promote the safety of the WHO recommendation is needed. The successful application of the Primaquine Roll Out Monitoring Pharmacovigilance Tool (PROMPT) demonstrates its potential as an important tool to rapidly generate locally acquired safety data and support pharmacovigilance in resource-limited settings.

Author: , , , , , , , , , , , , , , , ,
Publication date: July 2016
Source: Malaria Journal

Measuring the path toward malaria elimination

In many parts of the world, malaria elimination—defined by the World Health Organization (WHO) as the absence of locally acquired malaria cases in the country—is being considered as a target because of recent successes in reducing disease burden. Rigorous evaluation of malaria elimination programs is essential for financial and political support to be maintained. Yet such evaluation remains challenging, and appropriate metrics to ascertain “success” are needed.

Author: , , , , ,
Publication date: June 2014
Source: Science

Reactive Case Detection for Malaria Elimination: Real-Life Experience from an Ongoing Program in Swaziland

A study evaluating the effect of screening radius and other risk factors on the probability of detecting cases by reactive case detection, whereby individuals living in close proximity to passively detected cases are screened and treated, in Swaziland.

Author: , ,
Publication date: May 2013
Source: PLOS ONE