The study found the disappearance of chloroquine-resistant malaria after the removal of chloroquine drug pressure. Chloroquine may have a role for malaria prevention or treatment in Zambia and throughout the region in the future.
In Nchelenge, the co-existence of two highly anthropophagic vectors, present throughout the year, is likely to be driving the high malaria transmission evident in the district. The vectors here have been shown to be highly resistant to pyrethroids used for IRS during the study. Vector control interventions in this area would have to be multifaceted and district-wide for effective control of malaria.
Author: Chaponda M, Chilusu H, Coetzee M, Curriero FC, Jones CM, Lupiya J, Mbewe D, Muleba M, Mulenga M, Mwelwa I, Norris DE, Pinchoff J, Pringle JC, Shields T, Simubali L, Stevenson JC
Publication date: September 2016
Source: Parasites & Vectors
Malaria risk maps may be used to guide policy decisions on whether vector control interventions should be targeted and, if so, where. Active surveillance for malaria was conducted through household surveys in Nchelenge District, Zambia from April 2012 through December 2014. The final, validated model was used to predict and map malaria risk including a measure of risk uncertainty. Malaria risk in a high, perennial transmission setting is widespread but heterogeneous at a local scale, with seasonal variation. Targeting malaria control interventions may not be appropriate in this epidemiological setting.
A report on the findings and implications of a cross-sectional survey to determine the prevalence and intensity of infection among children under ten years, carried out in March-April 2012 in Nchelenge district, Zambia.