An assessment of the supply, programmatic use, and regulatory issues of single low-dose primaquine as a Plasmodium falciparum gametocytocide for sub-Saharan Africa.

This article outlines some of the barriers to single low-dose (SLD) primaquine use to stop P. falciparum transmission. In-country key informants revealed that the WHO weight-based recommendation to use SLD primaquine is challenging to implement in actual field settings, due in part to safety concerns involving G6PD deficiency and drug-drug interactions, among other factors.

Author: , , , , , , , ,
Publication date: May 2015
Source: Malaria Journal

Implementation of low dose primaquine as a gametocytocide in sub-Saharan Africa

A report that assesses opportunities and challenges for rolling out low-dose primaquine in sub-Saharan Africa, evaluating the current supply and production of primaquine, assessing country willingness to deploy low-dose primaquine, and identifying key barriers to implementation.

Author: , ,
Publication date: October 2013
Source: UCSF Global Health Sciences