Role of mass drug administration in elimination of Plasmodium falciparum malaria: a consensus modelling study

This study used consensus modeling to understand how to optimize the effects of mass drug administration in areas with low malaria transmission.

Author: , , , , , , , , , , , , , , , ,
Publication date: May 2017
Source: The Lancet Global Health

Country specific predictions of the cost-effectiveness of malaria vaccine RTS,S/AS01 in endemic Africa

This article discusses the high potential of the RTS,S vaccine for malaria in children. Additionally, results show that not only will the vaccine likely lead to positive health outcomes, but it is expected to do so in a cost-effective manner.

Author: , , , , ,
Publication date: January 2017
Source: Vaccine

The effect of mass mosquito trapping on malaria transmission and disease burden (SolarMal): a stepped-wedge cluster-randomised trial

Odour baits can attract host-seeking Anopheles mosquitoes indoors and outdoors. We assessed the effects of mass deployment of odour-baited traps on malaria transmission and disease burden. The unexpectedly low clinical incidence of malaria during roll-out led to an imprecise estimate of effectiveness from the clinical incidence data. The substantial effect on malaria prevalence is explained by reduction in densities of Anopheles funestus. Odour-baited traps might be an effective malaria intervention.

Author: , , , , , , , , , , , , ,
Publication date: September 2016
Source: The Lancet

Malaria intervention scale-up in Africa: effectiveness predictions for health programme planning tools, based on dynamic transmission modelling

Health improvements following malaria intervention scale-up vary with endemicity, seasonality, age and time. Statistical models can emulate epidemiological dynamics and inform strategic planning and target setting for malaria control.

Author: , , , , , , ,
Publication date: August 2016
Source: Malaria Journal

The effect of mass mosquito trapping on malaria transmission and disease burden (SolarMal): a stepped-wedge cluster-randomised trial

Odour baits can attract host-seeking Anopheles mosquitoes indoors and outdoors. This study assessed the effects of mass deployment of odour-baited traps on malaria transmission and disease burden.

Author: , , , , , , , , , , , , ,
Publication date: August 2016
Source: The Lancet

Distribution of malaria exposure in endemic countries in Africa considering country levels of effective treatment

When coverage of effective treatment is taken into account, higher country level estimates of average EIR and thus higher disease burden, are obtained for a given prevalence level, especially where access to treatment is high, and prevalence relatively low. These methods provide a unified framework for comparison of both the immediate and longer-term impacts of case management and of preventive interventions.

Author: , , , , , , ,
Publication date: April 2015

The effect of malaria control on Plasmodium falciparum in Africa between 2000 and 2015

This article, published in Nature found that Plasmodium falciparum infection prevalence in endemic Africa halved and the incidence of clinical disease fell by 40% between 2000 and 2015. Interventions have averted an estimated 663 (542–753 credible interval) million clinical cases since 2000. Insecticide-treated nets, the most widespread intervention, were by far the largest contributor (68% of cases averted).

Author: , , , , , , , , , , , , , , , , , , , , , , , , , ,
Publication date: September 2015
Source: Nature

The public health impact of malaria vaccine RTS,S in malaria endemic Africa: country-specific predictions using 18 month follow-up Phase III data and simulation models

Adding RTS,S to existing control programs, assuming continuation of current levels of malaria exposure and of health system performance, will potentially avert 100–580 malaria deaths and 45,000 to 80,000 clinical episodes per 100,000 fully vaccinated children over an initial 10-year phase.

Author: , , , ,
Publication date: July 2015
Source: Bio Med Central

A methodological framework for the improved use of routine health system data to evaluate national malaria control programs: evidence from Zambia

When improved through comprehensive parasitologically confirmed case reporting, HMIS data can become a valuable tool for evaluating malaria program scale-up. Using this approach, this article provides further evidence that increased ITN coverage is associated with decreased malaria morbidity and use of health services for malaria illness in Zambia.

Author: , , , , , , , , , , ,
Publication date: November 2014
Source: Population health metrics