Role of mass drug administration in elimination of Plasmodium falciparum malaria: a consensus modelling study

This study used consensus modeling to understand how to optimize the effects of mass drug administration in areas with low malaria transmission.

Author: , , , , , , , , , , , , , , , ,
Publication date: May 2017
Source: The Lancet Global Health

Hitting a Moving Target: A Model for Malaria Elimination in the Presence of Population Movement

Malaria elimination strategies may be unsuccessful if they focus only on vector biology, and ignore the mobility patterns of humans, particularly where the majority of infections are imported. In the first study in Mpumalanga Province in South Africa designed for this purpose, a metapopulation model is developed to assess the impact of their proposed elimination-focused policy interventions. The mathematical model predicts malaria elimination to be possible only when imported infections are treated before entry or eliminated at the source suggesting that a regionally focused strategy appears needed, for achieving malaria elimination in Mpumalanga and South Africa.

Author: , , ,
Publication date: December 2015
Source: PLOS One

Predicting the impact of border control on malaria transmission: a simulated focal screen and treat campaign

Reducing imported infections is a critical step in reaching malaria elimination. The model described in this paper predicts that the focal screen and treat campaign used at the South Africa-Mozambique border will not eliminate malaria on its own, but will reduce transmission substantially.

Author: , , ,
Publication date: July 2015
Source: Malaria Journal

Predicting the impact of border control on malaria transmission: a simulated focal screen and treat campaign

The reduction of imported infections is a vital element of an elimination strategy, particularly if a country is already experiencing high levels of imported infections. This simulation predicts that FSAT at the Mpumalanga–Maputo border will be unable to eliminate local malaria on its own, but may still play a key role in detecting and treating imported infections before they enter the country. Thus FSAT may form part of an integrated elimination strategy where a variety of interventions are employed together to achieve malaria elimination.

Author: , , ,
Publication date: July 2015
Source: Malaria Journal

Artemisinin resistance – modelling the potential human and economic costs

Artemisinin resistance poses a huge threat to the successes of malaria control in the past decade. This study quantifies the risks – providing estimates on how much additional mortality and health care costs to expect.

Author: , , , , , , , ,
Publication date: November 2014
Source: Malaria Journal