Clinical determinants of early parasitological response to ACTs in African patients with uncomplicated falciparum malaria: a literature review and meta-analysis of individual patient data

Artemisinin-resistant Plasmodium falciparum has emerged in the Greater Mekong sub-region and poses a major global public health threat. Slow parasite clearance is a key clinical manifestation of reduced susceptibility to artemisinin. This study was designed to establish the baseline values for clearance in patients from Sub-Saharan African countries with uncomplicated malaria treated with artemisinin-based combination therapies (ACTs).

Author:
Publication date: September 2015
Source: BMC Medicine
Permalink: http://www.makingmalariahistory.org/toolkit-resource/clinical-determinants-of-early-parasitological-response-to-acts-in-african-patients-with-uncomplicated-falciparum-malaria-a-literature-review-and-meta-analysis-of-individual-patient-data/

Artemisinin resistance – modelling the potential human and economic costs

Artemisinin resistance poses a huge threat to the successes of malaria control in the past decade. This study quantifies the risks – providing estimates on how much additional mortality and health care costs to expect.

Author: , , , , , , , ,
Publication date: November 2014
Source: Malaria Journal
Permalink: http://www.makingmalariahistory.org/toolkit-resource/artemisinin-resistance-modelling-the-potential-human-and-economic-costs/

Spread of Artemisinin Resistance in Plasmodium falciparum Malaria

Artemisinin resistance in Plasmodium falciparum has emerged in Southeast Asia and now poses a threat to the control and elimination of malaria. Mapping the geographic extent of resistance is essential for planning containment and elimination strategies.

Author: , , , , , , , , , , , , , , , , ,
Publication date: July 2014
Source: New England Journal of Medicine
Permalink: http://www.makingmalariahistory.org/toolkit-resource/spread-of-artemisinin-resistance-in-plasmodium-falciparum-malaria/

Emergence and spread of artemisinin resistance calls for intensified efforts to withdraw oral artemisinin-based monotherapy from the market

A report calling for intensified action to withdraw oral artemisinin-based monotherapy from the market and to promote the use of artemisinin-based combination therapy, in order to protect against further artemisinin resistance.

Author:
Publication date: May 2014
Source: World Health Organization
Permalink: http://www.makingmalariahistory.org/toolkit-resource/emergence-and-spread-of-artemisinin-resistance-calls-for-intensified-efforts-to-withdraw-oral-artemisinin-based-monotherapy-from-the-market/

Emergence and spread of artemisinin resistance calls for intensified efforts to withdraw oral artemisinin-based monotherapy from the market

An update on the latest status report on artemisinin resistance, providing an overview of WHO’s recommended regulatory actions and country progress to date to withdraw oral artemisinin-based monotherapy (oAMT) from the market.

Author:
Publication date: May 2014
Source: World Health Organization
Permalink: http://www.makingmalariahistory.org/toolkit-resource/emergence-and-spread-of-artemisinin-resistance-calls-for-intensified-efforts-to-withdraw-oral-artemisinin-based-monotherapy-from-the-market-2/

Status report on artemisinin resistance

A fact sheet providing the background on artemisinin resistance, updates on containment and surveillance progress, and the current status of resistance around the world.

Author:
Publication date: January 2014
Source: World Health Organization
Permalink: http://www.makingmalariahistory.org/toolkit-resource/status-report-on-artemisinin-resistance/