Perceptions of malaria and acceptance of rapid diagnostic tests and related treatment practises among community members and health care providers in Greater Garissa, North Eastern Province, Kenya

Using the setting of a pilot introduction of malaria RDTs in Greater Garissa, North Eastern Province, Kenya, this study aims to identify and understand perceptions regarding malaria diagnosis, with a particular focus on RDTs, and treatment among community members and health care workers (HCWs).

Author: , , , , , , , , , , ,
Publication date: December 2014
Source: Malaria Journal
Permalink: http://www.makingmalariahistory.org/toolkit-resource/perceptions-of-malaria-and-acceptance-of-rapid-diagnostic-tests-and-related-treatment-practises-among-community-members-and-health-care-providers-in-greater-garissa-north-eastern-province-kenya/

Perceptions of malaria and acceptance of rapid diagnostic tests and related treatment practises among community members and health care providers in Greater Garissa, North Eastern Province, Kenya.

Using the setting of a pilot introduction of malaria RDTs in Greater Garissa, North Eastern Province, Kenya, this study aims to identify and understand perceptions regarding malaria diagnosis, with a particular focus on RDTs, and treatment among community members and health care workers (HCWs).

Author: , , , , , , , , , , ,
Publication date: December 2014
Source: Malaria Journal
Permalink: http://www.makingmalariahistory.org/toolkit-resource/perceptions-of-malaria-and-acceptance-of-rapid-diagnostic-tests-and-related-treatment-practises-among-community-members-and-health-care-providers-in-greater-garissa-north-eastern-province-kenya-2/

Mass Screening and Treatment using a Falciparum-specific Rapid Diagnostic Test did not reduce malaria incidence in Zanzibar.

Seasonal increases in malaria continue in hotspots in Zanzibar. Mass screening and treatment (MSAT) may help reduce the reservoir of infection; however, it is unclear whether rapid diagnostic tests (RDT) detect a sufficient proportion of low-density infections to have impact on subsequent transmission. This study found that highly sensitive point-of-care diagnostic tools for detection of all human malaria species are needed to make MSAT an effective strategy in malaria pre-elimination settings.

Author: , , , , , , , , , , , , , ,
Publication date: November 2014
Source: Journal of Infectious Diseases
Permalink: http://www.makingmalariahistory.org/toolkit-resource/mass-screening-and-treatment-using-a-falciparum-specific-rapid-diagnostic-test-did-not-reduce-malaria-incidence-in-zanzibar/

High-resolution melting analysis reveals low Plasmodium parasitaemia infections among microscopically negative febrile patients in western Kenya.

Microscopy and rapid diagnostic tests (RDTs) are common tools for diagnosing malaria, but are deficient in detecting low Plasmodium parasitaemia. A novel molecular diagnostic tool (nPCR-HRM) that combines the sensitivity and specificity of nested PCR (nPCR) and direct PCR-high resolution melting analysis (dPCR-HRM) was developed. To evaluate patterns of anti-malarial drug administration when no parasites are detected, nPCR-HRM was employed to screen blood samples for low parasitaemia from febrile patients without microscopically detectable Plasmodium infections in a rural malaria-endemic setting.

Author: , , , , , ,
Publication date: November 2014
Source: PMC
Permalink: http://www.makingmalariahistory.org/toolkit-resource/high-resolution-melting-analysis-reveals-low-plasmodium-parasitaemia-infections-among-microscopically-negative-febrile-patients-in-western-kenya/

Rationale for short course primaquine in Africa to interrupt malaria transmission

A report of a meeting held in London in March 2012, discussing the existing evidence on the ability of primaquine to block malaria transmission, defining the roadblocks to the use of primaquine in Africa and to developing a roadmap to enable its rapid, safe and effective deployment.

Author: , ,
Publication date: October 2012
Source: Malaria Journal
Permalink: http://www.makingmalariahistory.org/toolkit-resource/rationale-for-short-course-primaquine-in-africa-to-interrupt-malaria-transmission/

The global pipeline of new medicines for the control and elimination of malaria

A study reviewing the global portfolio of new medicines in development against malaria, as of the summer of 2012.

Author: , ,
Publication date: September 2012
Source: Malaria Journal
Permalink: http://www.makingmalariahistory.org/toolkit-resource/the-global-pipeline-of-new-medicines-for-the-control-and-elimination-of-malaria/

Reductions in Artemisinin-Based Combination Therapy Consumption after the Nationwide Scale up of Routine Malaria Rapid Diagnostic Testing in Zambia

A report on rapid diagnostic test use, drug consumption, and diagnostic results from data collected in three Zambian health districts to determine the impact RDTs had on malaria case management over the period 2004–2009.

Author: , ,
Publication date: July 2012
Source: The American Journal of Tropical Medicine and Hygiene
Permalink: http://www.makingmalariahistory.org/toolkit-resource/reductions-in-artemisinin-based-combination-therapy-consumption-after-the-nationwide-scale-up-of-routine-malaria-rapid-diagnostic-testing-in-zambia/

Estimating the potential public health impact of seasonal malaria chemoprevention in African children

A study suggesting that seasonal malaria chemoprevention has the potential to avert several million malaria cases and tens of thousands of childhood deaths each year if successfully delivered to the populations at risk.

Author: , ,
Publication date: June 2012
Source: Nature Communications
Permalink: http://www.makingmalariahistory.org/toolkit-resource/estimating-the-potential-public-health-impact-of-seasonal-malaria-chemoprevention-in-african-children/

Got ACTs? Availability, price, market share and provider knowledge of anti-malarial medicines in public and private sector outlets in six malaria-endemic countries

A paper presenting supply side data from ACTwatch outlet surveys in Benin, the Democratic Republic of Congo (DRC), Madagascar, Nigeria, Uganda and Zambia.

Author: , ,
Publication date: October 2011
Source: Malaria Journal
Permalink: http://www.makingmalariahistory.org/toolkit-resource/got-acts-availability-price-market-share-and-provider-knowledge-of-anti-malarial-medicines-in-public-and-private-sector-outlets-in-six-malaria-endemic-countries/

Cost analysis of school-based intermittent screening and treatment of malaria in Kenya

A paper analyzing the costs of intermittent screening and treatment of malaria in schools, implemented as part of a cluster-randomized controlled trial on the Kenyan coast.

Author: , ,
Publication date: September 2011
Source: Malaria Journal
Permalink: http://www.makingmalariahistory.org/toolkit-resource/cost-analysis-of-school-based-intermittent-screening-and-treatment-of-malaria-in-kenya/