This article outlines some of the barriers to single low-dose (SLD) primaquine use to stop P. falciparum transmission. In-country key informants revealed that the WHO weight-based recommendation to use SLD primaquine is challenging to implement in actual field settings, due in part to safety concerns involving G6PD deficiency and drug-drug interactions, among other factors.
Author: Chen I, Cohen JM, Gosling R, Hwang J, Kandula D, Newman M, Poirot E, Rooney L, Shah R
Publication date: May 2015
Source: Malaria Journal