Imported Plasmodium falciparum and locally transmitted Plasmodium vivax: cross-border malaria transmission scenario in northwestern Thailand

Cross-border malaria transmission is an important problem for national malaria control programs. The epidemiology of cross-border malaria is further complicated in areas where Plasmodium falciparum and Plasmodium vivax are both endemic. By combining passive case detection data with entomological data, a transmission scenario on the northwestern Thai–Myanmar border where P. falciparum is likely driven by importation was described, whereas P. vivax is also locally transmitted. This study highlights the differences in the level of control required to eliminate P. falciparum and P. vivax from the same region.

Author: , , , , , , ,
Publication date: June 2017
Source: Malaria Journal
Permalink: http://www.makingmalariahistory.org/toolkit-resource/imported-plasmodium-falciparum-and-locally-transmitted-plasmodium-vivax-cross-border-malaria-transmission-scenario-in-northwestern-thailand/

Light manipulation of mosquito behaviour: acute and sustained photic suppression of biting activity in the Anopheles gambiae malaria mosquito

Host-seeking behaviors in anopheline mosquitoes are time-of-day specific, with a greater propensity for nocturnal biting. This study investigates how a short exposure to light presented during the night or late day can inhibit biting activity and modulate flight activity behavior.

Author: , , , , ,
Publication date: June 2017
Source: Parasites & Vectors
Permalink: http://www.makingmalariahistory.org/toolkit-resource/light-manipulation-of-mosquito-behaviour-acute-and-sustained-photic-suppression-of-biting-activity-in-the-anopheles-gambiae-malaria-mosquito/

Using remote sensing environmental data to forecast malaria incidence at a rural district hospital in Western Kenya

Two statistical models,a general additive model (GAM) and GAMBOOST model with boosted regression were contrasted by assessing their predictive accuracy in forecasting malaria admissions at lead times of one to three months. The GAMBOOST model at one-month lead time had the highest predictive skill during both the training and test periods and thus can be utilized in a malaria early warning system.

Author: , , ,
Publication date: June 2017
Source: Scientific Reports
Permalink: http://www.makingmalariahistory.org/toolkit-resource/using-remote-sensing-environmental-data-to-forecast-malaria-incidence-at-a-rural-district-hospital-in-western-kenya/

Do anti-malarials in Africa meet quality standards? The market penetration of non quality-assured artemisinin combination therapy in eight African countries

This paper uses national and sub-national medicine outlet surveys conducted in eight study countries (Benin, Kinshasa and Kantanga [Democratic Republic of the Congo, DRC], Kenya, Madagascar, Nigeria, Tanzania, Uganda and Zambia) between 2009 and 2015 to describe the non quality-assured ACT (QAACT) market and to document trends in availability and distribution of non-QAACT in the public and private sector.

Author: , , ,
Publication date: May 2017
Source: Malaria Journal
Permalink: http://www.makingmalariahistory.org/toolkit-resource/do-anti-malarials-in-africa-meet-quality-standards-the-market-penetration-of-non-quality-assured-artemisinin-combination-therapy-in-eight-african-countries/

Use of malaria RDTs in various health contexts across sub-Saharan Africa: a systematic review

Malaria rapid diagnostic tests (RDTs) increase the availability and feasibility of accurate diagnosis and may result in improved quality of care. Though RDTs are used in a variety of contexts, no studies have compared how well or effectively RDTs are used across these contexts. This review assesses the diagnostic use of RDTs in four different contexts: health facilities, the community, drug shops and schools.

Author: ,
Publication date: May 2017
Source: BMC Public Health
Permalink: http://www.makingmalariahistory.org/toolkit-resource/use-of-malaria-rdts-in-various-health-contexts-across-sub-saharan-africa-a-systematic-review/

Global survey of malaria rapid diagnostic test (RDT) sales, procurement and lot verification practices: assessing the use of the WHO–FIND Malaria RDT Evaluation Programme (2011–2014)

As malaria RDTs from different manufacturers can present wide variations, especially in terms of performance characteristics, and can be affected by sub-optimal transport or storage conditions, the use of the PT/LT Programme results as well as procurement and lot verification practices were assessed through a large-scale survey, gathering product-specific RDT sales and procurement data (2011–14 period) from a total of 32 manufacturers, 12 procurers, and 68 National Malaria Control Programmes (NMCPs).

Author: , , , , ,
Publication date: May 2017
Source: Malaria Journal
Permalink: http://www.makingmalariahistory.org/toolkit-resource/global-survey-of-malaria-rapid-diagnostic-test-rdt-sales-procurement-and-lot-verification-practices-assessing-the-use-of-the-who-find-malaria-rdt-evaluation-programme-2011-2014/

Immune resistance and tolerance strategies in malaria vector and non-vector mosquitoes

This study was designed to investigate the immune responses of An. coluzzii, An. arabiensis and An. quadriannulatus mosquitoes. The first two mosquito species are major vectors of malaria in sub-Saharan Africa, while the third is thought to be a non-vector.

Author: , ,
Publication date: April 2017
Source: Parasites & Vectors
Permalink: http://www.makingmalariahistory.org/toolkit-resource/immune-resistance-and-tolerance-strategies-in-malaria-vector-and-non-vector-mosquitoes/

Prospects for malaria control through manipulation of mosquito larval habitats and olfactory-mediated behavioural responses using plant-derived compounds

This review compiles information regarding the current status of knowledge on manipulation of larval ecology and chemical-mediated behaviour of adult mosquitoes with plant-derived compounds for controlling mosquito populations. Further, an update on the current advancements in technologies to improve longevity and efficiency of these compounds for field applications is provided.

Author: , , , ,
Publication date: April 2017
Source: Parasites & Vectors
Permalink: http://www.makingmalariahistory.org/toolkit-resource/prospects-for-malaria-control-through-manipulation-of-mosquito-larval-habitats-and-olfactory-mediated-behavioural-responses-using-plant-derived-compounds/

Geostatistical modelling of malaria indicator survey data to assess the effects of interventions on the geographical distribution of malaria prevalence in children less than 5 years in Uganda

This study analyzes 2014–15 Uganda Malaria Indicator Survey data to assess intervention effects on malaria prevalence among children less than five years of age and intervention effects at regional level, and estimate geographical distribution of malaria prevalence in the country.

Author: , , , , , ,
Publication date: April 2017
Source: PLOS One
Permalink: http://www.makingmalariahistory.org/toolkit-resource/geostatistical-modelling-of-malaria-indicator-survey-data-to-assess-the-effects-of-interventions-on-the-geographical-distribution-of-malaria-prevalence-in-children-less-than-5-years-in-uganda/

Comparative Transcriptomics of Malaria Mosquito Testes: Function, Evolution, and Linkage

A study wherein RNA sequencing of A. gambiae and A. merus carcass and testes was conducted to explore tissue- and species-specific patterns of gene expression. The data provide support for transcriptional repression of X-linked genes in the male germline, which likely drives demasculinization of the X chromosome.

Author: , , ,
Publication date: April 2017
Source: G3: GENES, GENOMES, GENETICS
Permalink: http://www.makingmalariahistory.org/toolkit-resource/comparative-transcriptomics-of-malaria-mosquito-testes-function-evolution-and-linkage/