Population genomics studies identify signatures of global dispersal and drug resistance in Plasmodium vivax

Signals of natural selection suggest that P. vivax is evolving in response to antimalarial drugs and is adapting to regional differences in the human host and the mosquito vector.

Author: , , , , , , , , , , , , , , , , , , , , , , , ,
Publication date: June 2016
Source: Nature Genetics
Permalink: http://www.makingmalariahistory.org/toolkit-resource/population-genomics-studies-identify-signatures-of-global-dispersal-and-drug-resistance-in-plasmodium-vivax/

Feasibility and Effectiveness of mHealth for Mobilizing Households for Indoor Residual Spraying to Prevent Malaria: A Case Study in Mali

The mobile-messaging approach, at US$8.62 per structure prepared, was both more costly and less effective than the door-to-door approach at US$1.08 per structure prepared. While literacy and familiarity with technology were major obstacles, it also became clear that by removing the face-to-face interactions between mobilizers and household residents, individuals were not as trusting or understanding of the mobilization messages.

Author: , , , , , , ,
Publication date: June 2016
Source: Global Health: Science and Practice
Permalink: http://www.makingmalariahistory.org/toolkit-resource/feasibility-and-effectiveness-of-mhealth-for-mobilizing-households-for-indoor-residual-spraying-to-prevent-malaria-a-case-study-in-mali/

Primaquine to reduce transmission of Plasmodium falciparum malaria in Mali: a single-blind, dose-ranging, adaptive randomised phase 2 trial

Single low doses of primaquine, when added to artemisinin-based combination therapy, might prevent transmission of Plasmodium falciparum malaria to mosquitoes. A single dose of 0·25 mg/kg primaquine, given alongside dihydroartemisinin–piperaquine, was safe and efficacious for the prevention of P falciparum malaria transmission in boys and men who are not deficient in G6PD

Author: , , , , , , , , , , , , , , , , , , ,
Publication date: June 2016
Source: The Lancet Infectious Diseases
Permalink: http://www.makingmalariahistory.org/toolkit-resource/primaquine-to-reduce-transmission-of-plasmodium-falciparum-malaria-in-mali-a-single-blind-dose-ranging-adaptive-randomised-phase-2-trial/

Assessing the effects of mosquito nets on malaria mortality using a space time model: a case study of Rufiji and Ifakara Health and Demographic Surveillance System sites in rural Tanzania

This study presents a Bayesian modelling framework for the analysis of the effect of ownership of at least one mosquito net at household on malaria mortality with environmental factors as confounder variables. Ownership of mosquito nets at household showed a significant impact on malaria mortality.

Author: , , , , , , ,
Publication date: May 2016
Source: Malaria Journal
Permalink: http://www.makingmalariahistory.org/toolkit-resource/assessing-the-effects-of-mosquito-nets-on-malaria-mortality-using-a-space-time-model-a-case-study-of-rufiji-and-ifakara-health-and-demographic-surveillance-system-sites-in-rural-tanzania/

Use of long-lasting insecticide-treated bed nets in a population with universal coverage following a mass distribution campaign in Uganda

Using data from the 2014 malaria indicator survey, this analysis estimated the proportion of the population with access to an LLIN that slept under one the night before the survey and factors associated with not using an LLIN in households that had achieved universal coverage.

Author: , ,
Publication date: April 2016
Source: Malaria Journal
Permalink: http://www.makingmalariahistory.org/toolkit-resource/use-of-long-lasting-insecticide-treated-bed-nets-in-a-population-with-universal-coverage-following-a-mass-distribution-campaign-in-uganda/

Potential for reduction of burden and local elimination of malaria by reducing Plasmodium falciparum malaria transmission: a mathematical modelling study

This study used a mathematical model of the transmission of Plasmodium falciparum malaria to explore the potential effect on case incidence and malaria mortality rates from 2015 to 2030 of five different intervention scenarios. These findings show that decreases in malaria transmission and burden can be accelerated over the next 15 years if the coverage of key interventions is increased.

Author: , , , , , , , , , ,
Publication date: April 2016
Source: The Lancet Infectious Diseases
Permalink: http://www.makingmalariahistory.org/toolkit-resource/potential-for-reduction-of-burden-and-local-elimination-of-malaria-by-reducing-plasmodium-falciparum-malaria-transmission-a-mathematical-modelling-study/

Exploring the spatiotemporal drivers of malaria elimination in Europe

Indicators relating to socio-economic improvements were strongly correlated with the decline of malaria in Europe, whereas those describing climatic and land use changes showed weaker relationships. Present-day malaria-elimination countries have now arrived at similar socio-economic indicator levels as European countries at the time malaria elimination was achieved, offering hope for achievement of sustainable elimination.

Author: , ,
Publication date: March 2016
Source: Malaria Journal
Permalink: http://www.makingmalariahistory.org/toolkit-resource/exploring-the-spatiotemporal-drivers-of-malaria-elimination-in-europe/

Predicting factors for malaria re-introduction: an applied model in an elimination setting to prevent malaria outbreaks

This study aimed to design an applicable model to monitor predicting factors of re-introduction of malaria in highly prone areas. Unpermitted immigrants from endemic neighbouring countries were determined as a pivotal factor (AHP score: 0.181). Moreover, quality of population movement (0.114), following malaria transmission season (0.088), average daily minimum temperature in the previous 8 weeks (0.062), an outdoor resting shelter for vectors (0.045), and rainfall (0.042) were determined.

Author: , , , , ,
Publication date: March 2016
Source: Malaria Journal
Permalink: http://www.makingmalariahistory.org/toolkit-resource/predicting-factors-for-malaria-re-introduction-an-applied-model-in-an-elimination-setting-to-prevent-malaria-outbreaks/

The Development of Surveillance Systems

This paper describes the redefinition of surveillance in the 1960s, asserting that its proper use in public health meant the systematic reporting of infectious diseases, the analysis and epidemiologic interpretation of data, and both prompt and widespread dissemination of results.

Publication date: February 2016
Source: American Journal of Epidemiology
Permalink: http://www.makingmalariahistory.org/toolkit-resource/the-development-of-surveillance-systems/

Strategies and approaches to vector control in nine malaria-eliminating countries: a cross-case study analysis

Country experiences in the Eliminating Malaria Case Study Series were reviewed to identify success factors on the road to elimination using a cross-case study analytic approach. Most countries aligned with integrated vector management, all programmes conducted entomological surveillance, and indoor residual spraying (IRS) and bednets were commonly used. There were several examples of severe reductions or halting of IRS coverage and subsequent resurgence of malaria.

Author: , , , , , ,
Publication date: January 2016
Source: Malaria Journal
Permalink: http://www.makingmalariahistory.org/toolkit-resource/strategies-and-approaches-to-vector-control-in-nine-malaria-eliminating-countries-a-cross-case-study-analysis/